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Updated: Jul 4, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
Published on: February 25, 2022
Hemodynamics "au contraire" despite diastolic flow reversal and angiographically severe aortic regurgitation
Sayed T Hussain1, Seher Iqbal, Syed N Ahmed
1Department of Internal Medicine, Division of Cardiology, University of Cincinnati, 231 Albert Sabin Way ML 0542, Cincinnati, OH 45267, USA. hussaist@ucmail.uc.edu
Abstract:
One of the commonly used parameters for evaluating aortic regurgitation is the rate of pressure decay data obtained from echocardiographic evaluation or cardiac catheterization. The measurement of the rate of equalization of pressure between the aorta and the left ventricle and its utility in the setting of aortic insufficiency has been validated. Intuitively, the Doppler equivalent, pressure half-time, is inversely related to the severity of regurgitation. However, this is a phenomenon dependent on multiple variables including blood pressure, heart rate, compliance of the receiving chamber, effects of vasopressors and the volume status of the patient. We report a case of unique hemodynamics obtained during cardiac catheterization due to low filling pressures that was further confounded by elevated systemic vascular resistance in a critically ill patient with angiographically severe aortic regurgitation.
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