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[Postmenopausal osteoporosis: when is it necessary to perform laboratory testing? Which testing strategy?]
1Unité de ménopause et des maladies osseuses métaboliques, hôpital Paule-de-Viguier, 330, avenue de Grande-Bretagne, 31059 Toulouse cedex 9, France.
Gynecologie, Obstetrique & Fertilite
|June 10, 2008
Summary
Secondary osteoporosis accounts for 10-20% of postmenopausal cases. Recommended lab tests include serum calcium, vitamin D, and complete blood count to identify underlying causes before treatment.
Area of Science:
- Endocrinology
- Bone Metabolism
- Geriatric Medicine
Context:
- Secondary causes of osteoporosis are frequently overlooked in postmenopausal women.
- Fragility fractures and unexplained low bone density warrant investigation into secondary causes.
Purpose:
- To outline recommended laboratory investigations for identifying secondary osteoporosis in postmenopausal women.
- To guide clinicians in selecting appropriate diagnostic tests before initiating osteoporosis therapy.
Summary:
- Secondary osteoporosis accounts for 10-20% of postmenopausal osteoporosis.
- Recommended tests include serum/urine calcium, phosphate, creatinine, 25-hydroxyvitamin D, CBC with ESR, and potentially protein electrophoresis and TSH.
- These investigations are crucial for women with recent fragility fractures or unexplained low bone mineral density.
Impact:
- Facilitates accurate diagnosis of secondary osteoporosis.
- Enables targeted therapeutic strategies, improving patient outcomes.
- Highlights the importance of comprehensive laboratory evaluation in managing osteoporosis.
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