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Arteries and Arterioles01:16

Arteries and Arterioles

Arteries, the vasculature responsible for transporting blood from the heart, possess robust walls capable of enduring the elevated pressures exerted by the heartbeat. Arteries near the heart are especially thick-walled and enriched with elastic fibers across their three tunics, classifying them as elastic or conducting arteries. These arteries, usually with a diameter exceeding 10 mm, are characterized by their ability to dilate in response to the blood pumped from the heart's ventricles and...
The Arch of Aorta01:10

The Arch of Aorta

The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
Encircling the heart, the coronary arteries form a ring-like structure before...
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the heart.
Arteries of the Head and Neck01:26

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Arteries of the Upper Limbs01:12

Arteries of the Upper Limbs

The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...

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Related Experiment Video

Updated: Jul 4, 2026

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches
06:51

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches

Published on: September 5, 2025

The arterial Windkessel.

Nico Westerhof1, Jan-Willem Lankhaar, Berend E Westerhof

  • 1Department of Physiology, Institute for Cardiovascular Research, ICaR-VU, VU University Medical Center, van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands. n.westerhof@vumc.nl

Medical & Biological Engineering & Computing
|June 11, 2008
PubMed
Summary

The Windkessel model, enhanced with characteristic impedance, accurately approximates ventricular afterload. This model is crucial for understanding arterial hemodynamics and cardiac function, despite limitations in assessing wave travel.

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Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter
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Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter

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Last Updated: Jul 4, 2026

Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches
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Multilevel Microdissection and Functional-Structural Profiling of Human Renal Arterial Branches

Published on: September 5, 2025

Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter
07:53

Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter

Published on: June 16, 2022

Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Hemodynamics

Background:

  • Frank's Windkessel model historically described arterial hemodynamics using resistance and compliance.
  • The original model adequately explained diastolic pressure decay but had limitations during systole.

Purpose of the Study:

  • To introduce characteristic impedance as a third element to the Windkessel model.
  • To enhance the model's ability to represent arterial hemodynamics, particularly during systole.

Main Methods:

  • Incorporation of characteristic impedance into the lumped Windkessel model.
  • Review of methods utilizing Windkessels for estimating total arterial compliance from pressure and flow data.

Main Results:

  • The enhanced Windkessel model, including characteristic impedance, links lumped parameters to transmission phenomena like wave travel.
  • Windkessel models provide physiologically interpretable parameters for input impedance and serve as a hydraulic load for isolated hearts.
  • The model is a simple and accurate approximation of ventricular afterload.

Conclusions:

  • The enhanced Windkessel model with characteristic impedance offers a more comprehensive representation of arterial hemodynamics.
  • While not suitable for distributed phenomena, it remains valuable for general circulation studies and estimating arterial compliance.
  • The model provides a simplified yet effective approximation of ventricular afterload in cardiovascular research.