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Updated: Jul 1, 2026

Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model

Ascending Aortic Constriction in Rats for Creation of Pressure Overload Cardiac Hypertrophy Model

Published on: June 29, 2014

Autar Singh Paintal: 24 September 1925 - 21 December 2004.

¹Department of Preclnical Veterinary Sciences, University of Edinburgh, Summerhall, Edinburgh.

Biographical Memoirs of Fellows of the Royal Society. Royal Society (Great Britain)

|June 12, 2008

Summary

This summary is machine-generated.

Pioneering physiologist Autar Paintal identified J receptors in the lung, detailing their sensory and reflex actions at varying altitudes. His research advanced understanding of cardiovascular and gastrointestinal sensory mechanisms.

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Area of Science:

Physiology
Neuroscience
Medical Research

Background:

Autar Paintal's career spanned institutions in India and Edinburgh.
He conducted foundational research on atrial and ventricular receptors.
His work also explored gastrointestinal sensory receptors.

Discussion:

Paintal's identification of J receptors was a significant contribution to respiratory physiology.
Characterization of J receptor reflex and sensory actions provided crucial insights.
Research was conducted under diverse environmental conditions, including high altitude.

Key Insights:

Precise characterization of atrial A and B fibres and ventricular afferent fibres.
Identification and functional analysis of lung J receptors.
Understanding sensory mechanisms in both normal and high-altitude environments.

Outlook:

Further research into J receptor modulation and clinical relevance.
Potential applications in understanding respiratory control and altitude-related disorders.
Building upon Paintal's legacy in sensory physiology research.