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Murine Bilateral Renal Lymphadenectomy
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Maurice Hugh Frederick Wilkins CBE: 15 December 1916 - 5 October 2004.

Struther Arnott1, T W B Kibble, Tim Shallice

  • 1Sir Alexander Fleming Building, Imperial College, London.

Biographical Memoirs of Fellows of the Royal Society. Royal Society (Great Britain)
|June 17, 2008
PubMed
Summary

Maurice Wilkins pioneered X-ray diffraction studies of DNA, providing crucial data for discovering the double helix structure. His foundational work enabled Watson and Crick

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Area of Science:

  • Biophysics
  • Molecular Biology
  • Structural Biology

Background:

  • Maurice Wilkins' early X-ray diffraction studies of DNA in 1950 yielded high-quality patterns.
  • These patterns suggested a simple, symmetrical, helical framework for the genetic material.

Discussion:

  • Wilkins' data significantly inspired J.D. Watson and F.H.C. Crick's DNA modeling efforts.
  • His work was pivotal, providing essential clues that led to the double helix model.

Key Insights:

  • Wilkins' research was fundamental to understanding DNA's duplex secondary structure.
  • He played a critical role in resolving technical challenges in DNA and RNA X-ray diffraction.

Outlook:

  • Wilkins' contributions underscore the importance of experimental data in theoretical model building.
  • His legacy highlights the collaborative nature of scientific discovery and perseverance.