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Updated: Jul 4, 2026

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Corneal Sensitivity Testing Procedure for Ophthalmologic and Optometric Patients
Published on: August 2, 2024
Factors affecting corneal hysteresis in normal eyes
Kazutaka Kamiya1, Mana Hagishima, Fusako Fujimura
1Department of Ophthalmology, University of Kitasato School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan. kamiyak-tky@umin.ac.jp
Summary
Corneal hysteresis (CH) is lower in eyes with thinner central corneal thickness (CCT) and higher intraocular pressure (IOP). These factors are crucial for refractive surgeons to consider for patient safety.
Area of Science:
- Ophthalmology
- Biomechanical properties of the cornea
Background:
- Corneal hysteresis (CH) is a measure of corneal biomechanical properties.
- Understanding factors influencing CH is important for ophthalmic procedures.
Purpose of the Study:
- To investigate the key factors influencing corneal hysteresis in healthy eyes.
- To identify clinical parameters correlated with CH variations.
Main Methods:
- 86 normal eyes from 43 healthy volunteers were analyzed.
- Corneal hysteresis was measured using the Ocular Response Analyzer.
- Multiple regression analysis was employed to determine influencing factors.
Main Results:
- Mean CH was 10.2 +/- 1.3 mmHg.
- Central corneal thickness (CCT) and intraocular pressure (IOP) were significant predictors of CH.
- Thinner CCT and higher IOP were associated with lower CH.
Conclusions:
- Lower corneal hysteresis is linked to thinner corneas and elevated intraocular pressure.
- Refractive surgeons should consider both CCT and IOP for biomechanical assessment prior to keratorefractive surgery.
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