Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This number is...
Friedman Two-way Analysis of Variance by Ranks01:21

Friedman Two-way Analysis of Variance by Ranks

Friedman's Two-Way Analysis of Variance by Ranks is a nonparametric test designed to identify differences across multiple test attempts when traditional assumptions of normality and equal variances do not apply. Unlike conventional ANOVA, which requires normally distributed data with equal variances, Friedman's test is ideal for ordinal or non-normally distributed data, making it particularly useful for analyzing dependent samples, such as matched subjects over time or repeated measures from...
Odds Ratio01:09

Odds Ratio

The odds ratio (OR) is a statistical measure used extensively in epidemiology and research to quantify the strength of association between exposure and outcome across different groups. Unlike relative risk, which compares the probabilities of an event occurring, the odds ratio compares the odds of an event occurring in the exposed group to the odds of it occurring in the unexposed group. The odds, in this context, are calculated as the probability of the event happening divided by the...
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...
Statistical Analysis: Overview01:11

Statistical Analysis: Overview

When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
Statistical Hypothesis Testing01:16

Statistical Hypothesis Testing

Hypothesis testing is a critical statistical procedure facilitating informed, evidence-based decisions. It begins with a hypothesis, which is a tentative explanation, or a prediction about a population parameter. This hypothesis can be either a null hypothesis (H0), indicating no effect or difference, or an alternative hypothesis (Ha), suggesting an effect or difference.
Statistical significance measures the probability that an observed result occurred by chance. If this probability, known as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Labor Supply, Risk Aversion, and Conflict Uncertainty.

Risk analysis : an official publication of the Society for Risk Analysis·2026
Same journal

Attribution as a Conditional Reasoning Step in Multifactorial Risk Analysis and Decision-Making.

Risk analysis : an official publication of the Society for Risk Analysis·2026
Same journal

Risk Without Values: Including Indigenous Perspectives in Climate Risk Assessments.

Risk analysis : an official publication of the Society for Risk Analysis·2026
Same journal

What if the Risk Manager is Malevolent?

Risk analysis : an official publication of the Society for Risk Analysis·2026
Same journal

Effectiveness of Communication Strategies on Risk Perception in Technoscience: A Systematic Literature Review Through an Argumentation Theory Approach.

Risk analysis : an official publication of the Society for Risk Analysis·2026
Same journal

The Roles of Place Attachment and Geovisualizations on Hurricane Storm Surge Risk Perceptions and Behavioral Intentions.

Risk analysis : an official publication of the Society for Risk Analysis·2026

Related Experiment Video

Updated: Jul 4, 2026

Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents
07:05

Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents

Published on: September 10, 2018

Bayesian reanalysis of the Challenger O-ring data.

Coire J Maranzano1, Roman Krzysztofowicz

  • 1The Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Rd., Laurel, MD 20723-6099, USA. Coire.Maranzano@jhuapl.edu

Risk Analysis : an Official Publication of the Society for Risk Analysis
|June 17, 2008
PubMed
Summary

A Bayesian forecasting model quantifies O-ring damage risk for the Space Shuttle Challenger launch. This approach accurately predicts damage risk at lower temperatures, unlike previous methods.

More Related Videos

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments
08:12

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments

Published on: March 1, 2022

Related Experiment Videos

Last Updated: Jul 4, 2026

Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents
07:05

Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents

Published on: September 10, 2018

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments
08:12

A Psychophysics Paradigm for the Collection and Analysis of Similarity Judgments

Published on: March 1, 2022

Area of Science:

  • Risk analysis
  • Statistical modeling
  • Aerospace engineering

Background:

  • The Space Shuttle Challenger disaster highlighted critical O-ring failures.
  • Previous analyses struggled with extrapolating data beyond observed temperature ranges.
  • Accurate forecasting of O-ring performance at low temperatures is crucial for flight safety.

Purpose of the Study:

  • To develop a Bayesian forecasting model for quantifying O-ring damage uncertainty.
  • To address the challenge of extrapolating predictive models to unprecedented low temperatures.
  • To integrate expert judgment with empirical data for improved risk assessment.

Main Methods:

  • A Bayesian forecasting model was developed to assess O-ring damage probability.
  • A novel method for extrapolating model inputs using expert judgment was introduced.
  • The model allows for assessing posterior probabilities of O-ring damage under various temperature conditions.

Main Results:

  • The Bayesian model provides a robust framework for quantifying uncertainty in O-ring postflight states.
  • Expert judgment was effectively incorporated to handle extrapolation beyond the sampled temperature range.
  • The model demonstrates superior performance compared to generalized linear models for out-of-sample predictions.

Conclusions:

  • Bayesian forecasting offers a more reliable method for risk analysis, especially when extrapolating data.
  • The developed model effectively combines empirical evidence with expert knowledge for decision-making.
  • This approach enhances the safety assessment of space missions by providing better uncertainty quantification.