Related Experiment Video
Updated: Jul 4, 2026
06:23
Assessment of Plasma Coagulation on Liver Tissue in a Large Animal Model In Vivo
Published on: August 4, 2018
Second-generation argon plasma coagulation: two-center experience with 600 patients.
Hendrik Manner1, Markus D Enderle, Oliver Pech
1Department of Internal Medicine II, HSK Wiesbaden, Wiesbaden, Germany. HSManner@gmx.de
Journal of Gastroenterology and Hepatology
|June 21, 2008
Summary
Second-generation argon plasma coagulation (APC) modes are safe and effective for gastrointestinal diseases, with minor complications in 9-21% and major complications in 1-7% of patients. Preventive measures are recommended to minimize risks.
Area of Science:
- Gastroenterology
- Medical Devices
- Endoscopic Technology
Background:
- Second-generation argon plasma coagulation (APC 2/VIO APC) represents an advancement over the first-generation ICC/APC 300 system.
- Limited data previously existed on the clinical application and efficacy of APC 2 modes ('forced', 'pulsed', 'precise').
Purpose of the Study:
- To analyze the characteristics and clinical data of second-generation APC (APC 2) modes.
- To develop recommendations for the daily use of APC 2 in gastroenterological practice.
Main Methods:
- Analysis of fundamental data on APC 2 mode characteristics.
- Review of clinical data from over 600 patients treated in two high-volume endoscopy centers.
Main Results:
- APC 2 offers a wider range of settings, including variable APC modes and power settings (1-120 W), compared to the ICC system.
- Minor complications occurred in 9-21% of patients, and major complications in 1-7% across various gastrointestinal diseases treated with APC 2 modes.
Conclusions:
- The different APC 2 modes demonstrated safety and effectiveness in a large, diverse patient cohort across two centers.
- Recommendations for preventive measures before and during clinical application are crucial to minimize potential complications.
