Historical review of carpal tunnel syndrome

The first description of median nerve compression in the carpal tunnel goes back to 1854, but it was only a century later that the term "carpal tunnel syndrome" (CTS) appeared in print. Until then, patients with symptoms, which we now know were due to CTS, were sometimes diagnosed as having acroparaesthesia, and at other times compression of the motor branch of the median nerve or the brachial plexus. The first description of an operation to open the carpal tunnel goes back to 1933, but only with Brain and Phalen was idiopathic CTS defined from both clinical and anatomopathological viewpoints. Since 1960, CTS has become the most frequently diagnosed of peripheral compression-induced neuropathies. The last part of this paper reports the latest theories giving an aetiological explanation of cases of CTS until now considered to be idiopathic.