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Updated: Jul 4, 2026

Split Point Analysis and Uncertainty Quantification of Thermal-Optical Organic/Elemental Carbon Measurements
Published on: September 7, 2019
Uncertainties of method performance statistics based on a balanced completely randomized model interlaboratory study
1U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition, Communication and Emergency Response, Division of Public Health and Biostatistics, Biostatistics Branch, College Park, MD 20740-3835, USA. fdmc5100@yahoo.com
Abstract:
Using exact and asymptotic distributions, formulas were developed to derive population variances and uncertainties, and their corresponding unbiased estimates, for the method performance statistics, i.e., the sample mean (y..), the repeatability variance and standard deviation and (s2r and sr), and the reproducibility variance and standard deviation (s2R and sR) and obtained from collaborative study of an analytical method.
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