[Research on formulation process of Yigong capsule]

Area of Science:

• Pharmaceutical Sciences
• Materials Science

Context:

• Yigong capsule formulation requires optimization for stability.
• Moisture absorption is a critical factor affecting capsule integrity.

Purpose:

• To identify the optimal supplementary material and formulation process for Yigong capsules.
• To enhance the anti-water absorbability of the Yigong capsule formulation.

Summary:

• The study evaluated critical relative humidity, moisture absorption curves, and angle of repose to select the best formulation process.
• Mixing PH102 microcellulose with medicinal powder proved feasible, improving moisture absorption.
• The optimized process ensures production and storage humidity remains below 64%.

Impact:

• The developed formulation process is simple, feasible, and enhances Yigong capsule stability.
• This research provides a robust formulation strategy for improved Yigong capsule quality.