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Updated: Jul 3, 2026

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice
Published on: February 1, 2022
Surgical restoration of the postinfarction dilated ventricle
Constantine L Athanasuleas1, Gerald D Buckberg
1University of Alabama Birmingham, Birmingham, AL, USA.
Abstract:
Surgical restoration of the failing heart is related to rebuilding cardiac architecture and linked to: (a) understanding that the structure of the failing dilated heart involves changing the normal elliptic shape toward a dilated spherical form; (b) recognizing the anatomic fiber orientation framework and its functional implications; (c) establishing imaging measurement guidelines to determine indications for surgical intervention that focus upon volume and remote muscle evaluation rather than ejection fraction; and (d) summarizing left ventricular restoration results whereby rebuilding normal elliptic configuration improves function, reduces ventricular arrhythmias, alleviates mechanical dyssynchrony, and causes progressive improvement that extends long-term prognosis.
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