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Related Experiment Video

Updated: Jul 3, 2026

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

Published on: January 9, 2020

Interaction between warfarin and tamoxifen: a case report.

D Mishra¹, R Paudel, P V Kishore

¹Department of Medicine, Manipal Teaching Hospital, Manipal College of Medical Sciences, Pokhara, Nepal. deepakmishra46@hotmail.com

Kathmandu University Medical Journal (KUMJ)

|July 8, 2008

Summary

Warfarin and tamoxifen drug interaction can increase bleeding risk. Careful monitoring of coagulation is crucial when these medications are used together, especially in diverse populations.

Related Experiment Videos

Last Updated: Jul 3, 2026

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects

Published on: January 9, 2020

Area of Science:

Pharmacology
Oncology
Clinical Medicine

Background:

Warfarin is a widely prescribed anticoagulant.
Tamoxifen is a standard treatment for estrogen-receptor-positive breast cancer.
Drug interactions between warfarin and tamoxifen are known, potentially increasing bleeding risk.

Observation:

A case of acute drug interaction between warfarin and tamoxifen is presented.
Previous reports of this interaction are primarily from Caucasian populations.
This case highlights a potentially rapid onset of the interaction.

Findings:

Co-administration of warfarin and tamoxifen necessitates vigilant monitoring of coagulation parameters.
The interaction can lead to an increased tendency for bleeding.
Clinical vigilance is required to manage this drug interaction effectively.

Implications:

Healthcare providers should be aware of the potential for warfarin-tamoxifen interaction.
Close monitoring of the coagulation profile is recommended for patients on both medications.
Further research may be needed to understand this interaction across different ethnicities.