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Topiramate induced bilateral angle-closure glaucoma
S K Singh1, S S Thapa, B P Badhu
1Mechi Eye Care Centre, Birtamod, Jhapa, Nepal. sanjaysinghnepal@yahoo.com
Kathmandu University Medical Journal (KUMJ)
|July 8, 2008
Summary
Topiramate can cause severe eye problems like angle-closure glaucoma. Early detection and treatment, including stopping the medication, can successfully manage this serious ophthalmic side effect.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Topiramate is a widely prescribed antiepileptic and migraine prophylactic medication.
- Ophthalmic side effects of topiramate, though rare, necessitate clinical awareness.
Observation:
- A case of bilateral angle-closure glaucoma induced by topiramate is reported.
- This represents the first such case documented in Nepal.
Findings:
- Discontinuation of topiramate was crucial for management.
- Combined therapy with anti-glaucoma medication and atropine eye drops led to successful resolution.
Implications:
- Highlights the potential for severe ophthalmic complications with topiramate use.
- Emphasizes the importance of prompt recognition and intervention for topiramate-induced glaucoma.
- Contributes to the understanding of topiramate's adverse effect profile in clinical practice.
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