Protein-losing enteropathy detected by Tc-99m-MDP abdominal scintigraphy

This case report describes the incidental finding of intestinal leakage during bone scan imaging with Tc-99m methylene diphosphonate (MDP) in a patient with previously diagnosed protein-losing enteropathy (PLE). Most radiopharmaceuticals reported in the literature that are useful for making this diagnosis are not generally available for clinical use in the United States. This report suggests that Tc-99m-MDP is useful for confirming the diagnosis of PLE although further investigations are indicated to determine the accuracy of this method.