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Pediatric movement disorders: an update
David S Wolf1, Harvey S Singer
1Department of Neurology, Johns Hopkins Hospital, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287-1000, USA.
Insights
This review highlights recent advances in pediatric movement disorders, including motor stereotypies, restless legs syndrome, and infantile masturbation. Progress has been made in understanding autoimmune conditions like Sydenham's chorea, though PANDAS remains debated.
Area of Science:
- Neurology
- Pediatrics
- Movement Disorders
Background:
- Pediatric movement disorders encompass a wide spectrum, often characterized by intermittent and hyperkinetic symptoms.
- Several under-recognized conditions and autoimmune disorders require further investigation.
Purpose of the Study:
- To review recent findings in motor stereotypy disorder, restless legs syndrome, and infantile masturbation.
- To discuss advances in autoimmune movement disorders, specifically Sydenham's chorea and PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection).
Main Methods:
- Literature review of recent findings.
- Discussion of diagnostic criteria, epidemiology, pathogenesis, and treatment.
Main Results:
- Motor stereotypies are common in children and can be persistent.
- Infantile masturbation is frequently misdiagnosed as seizures or dystonia.
- Restless legs syndrome is prevalent in children, with established diagnostic criteria.
- Advances in Sydenham's chorea are noted, while PANDAS remains controversial.
Conclusions:
- Significant progress has been achieved in understanding paroxysmal movement disorders.
- Further research is needed for conditions like PANDAS.
- Accurate diagnosis and management of pediatric movement disorders are improving.
Purpose Of Review:
Pediatric movement disorders the represent a broad range of disorders, the majority of which are intermittent and hyperkinetic. The goal of this review is to discuss recent findings in several under-recognized conditions (motor stereotypy disorder, restless legs syndrome, and infantile masturbation) as well as the area of autoimmune movement disorders [Sydenham's chorea and PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection)].
Recent Findings:
Advances to be discussed include clarification of symptoms, diagnostic clues, epidemiology, pathogenesis, and treatment.
Summary:
Significant progress has been made in the study of several paroxysmal movement disorders. Motor stereotypies can occur in typical children and persist over time. Infantile masturbation is often misdiagnosed for seizures or dystonia. Restless leg syndrome is a relatively common problem in children and established criteria are available. Advances have been made in the hallmark autoimmune disorder Sydenham's chorea, but PANDAS remains controversial.
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