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Updated: Jul 3, 2026

Dissection of the Endolymphatic Sac from Mice
Published on: March 29, 2021
Functional blood flow patterns of the endolymphatic sac in the rat
1Department of Otolaryngology, Head & Neck Surgery, Rigshospitalet, Copenhagen, Denmark. morten_friis@hotmail.com
Conclusion:
Visualization of the endolymphatic sac vascular network under video fluorescence microscopy showed a typical microvascular organization. The microvascular arrangement and the microcirculation may reflect a functional state of the endolymphatic sac. Damage or change of the blood circulation following endolymphatic sac surgery is discussed.
Objectives:
To visualize and study the dynamic microcirculation of the endolymphatic sac in live rats.
Method:
An experimental animal study using in vivo video fluorescence microscopy.
Results:
Visualization of the endolymphatic sac vascular network showed a typical microvascular organization. The endolymphatic sac appeared hypervascular and independent from other vascular systems. The microcirculation of the endolymphatic sac was supplied by ramification of a single artery, while venous trunks perpendicular to the length of the endolymphatic sac served as return paths for the microcirculation. The blood flow pattern was highly variable between rats.

