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[Tracheopathia osteoplastica].

B Liétin1, J-F Vellin, L Bivahagumye

  • 1Service d'ORL et de chirurgie de la face et du cou, CHU de Clermont-Ferrand, BP 69, 63003 Clermont-Ferrand cedex 1, France.

Annales D'Oto-Laryngologie Et De Chirurgie Cervico Faciale : Bulletin De La Societe D'Oto-Laryngologie Des Hopitaux De Paris
|July 11, 2008
PubMed
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Tracheopathia osteoplastica is a rare condition causing bone and cartilage nodules in the trachea. Diagnosis is often incidental, and treatment is symptomatic, as the condition typically does not affect prognosis.

Area of Science:

  • Respiratory Medicine
  • Pathology
  • Otolaryngology

Background:

  • Tracheopathia osteoplastica (TO) is a rare condition characterized by the formation of osteocartilaginous nodules within the tracheal wall.
  • Its etiology and pathophysiology remain largely unknown, contributing to diagnostic and therapeutic challenges.

Observation:

  • A case of TO was diagnosed incidentally during laryngotracheoscopy for difficult intubation in a patient with a history of nasal polyposis.
  • The patient presented with a dystrophic trachea featuring whitish nodules and swelling.

Findings:

  • Diagnostic workup, including CT scans and various laboratory tests, yielded nonspecific results.
  • Potential etiopathogenic factors include chronic upper airway inflammation (e.g., ozena), endocrine factors, autoimmune conditions, toxic exposures, or tracheobronchial amyloidosis.

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  • Bronchial microbiology is often positive, with common findings of Klebsiella ozaenae or Pseudomonas aeruginosa.

    • Implications:

    • TO is typically discovered incidentally and progresses slowly, usually not compromising the vital prognosis.
    • Current treatment is primarily symptomatic, with limited surgical interventions described in the literature.
    • Further research is needed to elucidate the etiology and pathophysiology of TO for improved management strategies.