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Updated: Jun 28, 2025

Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung
Published on: January 22, 2021
Cytobacteriological testing of drainage pus from peritonsillar abscess is not contributive in clinical practice: A
L Bivahagumye1, V Gosselet2, S Cambier3
1Service d'ORL et chirurgie cervico-faciale, CRNH, unité de nutrition humaine, université de Clermont-Auvergne, CHU de Clermont-Ferrand, 28, rue Montalembert, 63000 Clermont-Ferrand, France; Inra, CRNH, unité de nutrition humaine, université Clermont Auvergne, Auvergne, Clermont-Ferrand, France.
Purpose:
Peritonsillar abscess (PTA) is a frequent pathology. Treatment consists in drainage of the collection, associated to probabilistic antibiotic therapy. The usefulness of cytobacteriological testing (CBT) of the drainage pus is controversial.
Material And Methods:
A retrospective study of patients managed for PTA between 2013 and 2020 in our university hospital was performed. The main objective was to assess the usefulness of CBT in the management of PTA. The secondary objectives were to determine the bacteriological profile involved in the onset of PTA and to assess the rate of bacterial resistance to antibiotics prescribed on a probabilistic basis.
Results:
The study included 207 patients: 70 outpatients (33%) and 137 inpatients (67%). Probabilistic antibiotic therapy was implemented in 100% of patients. CBT was performed systematically and was negative in 106 patients, revealing oropharyngeal flora in 40% of cases, polymicrobial flora in 50% and sterile samples in 10%. In the 101 patients with positive CBT, the bacteria isolated were penicillin-sensitive in 99%. All patients were successfully treated. In the light of the bacteriological results, no changes were made to the probabilistic antibiotic therapy introduced on admission.
Conclusion:
CBT on drainage pus had no impact on the management of PTA. CBT is therefore unnecessary in patients with no comorbidities and no signs of severity at admission.
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