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Related Concept Videos

Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...

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Related Experiment Video

Updated: Jul 3, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

[Retroperitoneal fibrosis, M. Ormond, periaoartitis, ...?].

Bruno Vogt1, Pascal Meier, Michel Burnier

  • 1Service de Néphrologie et d'Hypertension, Centre Médical Universitaire Vaudois (CHUV)-Université de Lausanne, Rue du Bugnon 17, Lausanne. bruno.vogt@chuv.ch

Therapeutische Umschau. Revue Therapeutique
|July 16, 2008
PubMed
Summary
This summary is machine-generated.

Retroperitoneal fibrosis, also known as Morbus Ormond, is a rare inflammatory condition affecting the retroperitoneal space and aorta. Treatment involves steroids and immunosuppressants, with variable patient responses.

Related Experiment Videos

Last Updated: Jul 3, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
06:27

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice

Published on: July 20, 2022

Area of Science:

  • Nephrology
  • Vascular Surgery
  • Rheumatology

Context:

  • Retroperitoneal fibrosis (RPF), or Morbus Ormond, is a rare condition characterized by inflammatory fibrosis in the retroperitoneal space.
  • It frequently involves the abdominal aorta and common iliac arteries, potentially leading to aneurysmal dilation.
  • The etiology remains unclear, but autoimmune mechanisms are implicated.

Purpose:

  • To summarize the current understanding of retroperitoneal fibrosis.
  • To highlight its clinical presentation, complications, and management strategies.

Summary:

  • RPF presents with non-specific symptoms like abdominal, flank, or back pain.
  • A key complication is ureteral obstruction, causing obstructive nephropathy.
  • Diagnosis relies on clinical symptoms, inflammatory markers, and imaging (CT/MRI).

Impact:

  • Due to its rarity and varied presentation, no randomized controlled trials exist for RPF.
  • Treatment involves corticosteroids, often combined with immunosuppressants (azathioprine, cyclophosphamide).
  • Therapeutic responses are variable, necessitating individualized treatment plans.