Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Endoscopic therapy for GERD: does it have a future?

Marvin Ryou1, Christopher C Thompson

  • 1Brigham & Women's Hospital, Division of Gastroenterology, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Current Gastroenterology Reports
|July 16, 2008
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hybrid Laparoscopic-Endoscopic Partial Jejunal Diversion with Magnetic Anastomosis in Obesity and Type 2 Diabetes: Durable 3-Year Metabolic Results.

Endoscopy international open·2026
Same author

Four-Year Outcomes of Duodeno-Ileal Bipartition Using Self-Forming Magnets: The Sutureless Neodymium Anastomosis Procedure (SNAP) for Obesity and Type 2 Diabetes.

Obesity surgery·2026
Same author

Metabolic mechanisms of duodeno-ileal diversion: early bile acid and incretin signalling predict glycaemic outcomes.

Gut·2026
Same author

Percutaneous needle decompression for endoscopic iatrogenic pneumoperitoneum: assessment of safety and efficacy in real world practice.

Gut·2026
Same author

Impact of Endoscopic Bariatric and Metabolic Therapies on Chronic Kidney Disease in Patients with Impaired Glycemic Control.

Obesity surgery·2026
Same author

Endoscopic gastric remodeling and its histologic impact on metabolic dysfunction-associated steatohepatitis: a 12-month prospective study.

Gastrointestinal endoscopy·2026
Same journal

Management of Common Bile Duct Stones: Current Approaches and Evolving Endoscopic Strategies.

Current gastroenterology reports·2026
Same journal

Solitary Rectal Ulcer Syndrome Revisited: A Comprehensive Narrative Review.

Current gastroenterology reports·2026
Same journal

The Microbiome and Esophageal Disease: Where Are We Now?

Current gastroenterology reports·2026
Same journal

Fermented Durian Tempoyak as a Source of Probiotics for Colorectal Cancer Prevention through Gut Microbiome Modulation.

Current gastroenterology reports·2026
Same journal

A Practical Guide to Incorporating Novel Barrett's Screening/Surveillance Tools into Clinical Practice.

Current gastroenterology reports·2026
Same journal

The Role of Endoscopic Ultrasound in the Diagnosis and Management of Congenital Gastrointestinal and Pancreaticobiliary Conditions.

Current gastroenterology reports·2026
See all related articles

Gastroesophageal reflux disease (GERD) patients refractory to proton pump inhibitors (PPIs) need new treatments. Endoscopic GERD therapy offers a promising alternative to PPIs and surgery, but requires further study.

Area of Science:

  • Gastroenterology
  • Minimally Invasive Surgery

Background:

  • Gastroesophageal reflux disease (GERD) affects many patients.
  • Proton pump inhibitor (PPI) therapy is the standard treatment but is ineffective for approximately 20% of patients and is costly.
  • Surgical options like fundoplication carry risks and are not suitable for all patients.

Purpose of the Study:

  • To review the evolution of endoscopic therapies for GERD.
  • To describe current endoscopic devices for GERD treatment.
  • To explore the future potential of GERD endotherapy.

Main Methods:

  • Review of existing literature on GERD endotherapies.
  • Discussion of various endoscopic techniques including radiofrequency ablation, bulking agents, and tissue apposition.
  • Analysis of the current status and future directions of GERD endotherapy.

Related Experiment Videos

Main Results:

  • Several endoscopic methods have been developed for GERD treatment.
  • These methods aim to reduce reliance on PPIs and avoid surgical risks.
  • The field of GERD endotherapy is emerging and shows promise.

Conclusions:

  • Endoscopic therapy for GERD is a developing field.
  • Further rigorous, sham-controlled, long-term studies are needed.
  • Endotherapies may become viable alternatives for GERD management.