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Updated: Jul 3, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
Published on: July 29, 2007
The amyotrophic lateral sclerosis center: a model of multidisciplinary management
Angeli S Mayadev1, Michael D Weiss, B Jane Distad
1Department of Physical Medicine and Rehabilitation, University of Washington Medical Center, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Abstract:
Amyotrophic lateral sclerosis (ALS) is a devastating, progressive motor neuron disorder that poses a myriad of clinical problems. Patients who have ALS are best cared for in a multidisciplinary fashion, with involvement of clinicians from various specialties, including neurology, physical medicine and rehabilitation, pulmonary medicine, clinical nurse specialists or nurse practitioners, physical and occupational therapists, speech language pathologists, dietitians, psychologists, social workers, and case managers. This article provides a summary of the current research into the rehabilitation of ALS, including the role of exercise, spasticity management, mood disorders, pain, and palliative care.
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