Related Experiment Video
Updated: Jul 3, 2026

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
Published on: October 3, 2025
PET & SPECT instrumentation
Virginia C Spanoudaki1, Sibylle I Ziegler
1Klinikum rechts der Isar, Nuklearmedizinische Klinik und Poliklinik der TU München, Ismaninger Str. 22, 81675, München, Germany. v.spanoudaki@lrz.tu-muenchen.de
Abstract:
The nuclear medical imaging methods, positron emission tomography (PET) and single photon emission computed tomography (SPECT), utilize the detection of gamma rays leaving the body after a radioactive tracer has been administered. The sensitivity of PET allows the detection of picomolar tracer amounts in vivo and current technology offers millimeter (PET) or submillimeter (SPECT) spatial resolution. These techniques are used in clinical and preclinical applications. The basic principles of gamma ray detection and image generation in PET and SPECT are summarized in this chapter. Furthermore, effects causing degradation of image quality are discussed.
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