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Polarization-Sensitive Two-Photon Microscopy for a Label-Free Amyloid Structural Characterization
Published on: September 8, 2023
Simulation of polarization-sensitive optical coherence tomography images by a Monte Carlo method
Igor Meglinski1, Mikhail Kirillin, Vladimir Kuzmin
1Cranfield Health, Cranfield University, Cranfield, UK. i.meglinski@cranfield.ac.uk
Abstract:
We introduce a new Monte Carlo (MC) method for simulating optical coherence tomography (OCT) images of complex multilayered turbid scattering media. We demonstrate, for the first time of our knowledge, the use of a MC technique to imitate two-dimensional polarization-sensitive OCT images with nonplanar boundaries of layers in the medium like a human skin. The simulation of polarized low-coherent optical radiation is based on the vector approach generalized from the iterative procedure of the solution of Bethe-Saltpeter equation. The performances of the developed method are demonstrated both for conventional and polarization-sensitive OCT modalities.
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