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Deep brain stimulation for movement disorders and its neuropsychological implications
H M Mehdorn1, S Goebel, D Falk
1Department of Neurosurgery, University Clinics of Schleswig-Holstein Kiel, Kiel, Germany. mehdorn@nch.uni-kiel.de
Acta Neurochirurgica. Supplement
|July 23, 2008
Summary
Deep brain stimulation (DBS) is a therapy for movement disorders. Neuropsychological evaluations are crucial before and after DBS surgery to understand effects on cognitive and emotional functions and identify at-risk patients.
Area of Science:
- Neurology
- Neurosurgery
- Neuropsychology
Background:
- Deep brain stimulation (DBS) is increasingly used for movement disorders.
- Parkinson's disease (PD) and its treatments can cause neuropsychological changes.
- Surgical intervention for DBS affects motor, cognitive, and limbic functions, posing risks.
Purpose of the Study:
- To emphasize the importance of neuropsychological evaluation in DBS therapy.
- To highlight potential adverse effects on cognitive and emotional domains.
- To identify patient populations at higher risk for negative outcomes.
Main Methods:
- Review of existing literature on DBS and neuropsychological alterations in movement disorders.
- Analysis of the impact of DBS on cognitive and emotional functions.
- Discussion of the role of pre- and postoperative neuropsychological assessments.
Main Results:
- Neuropsychological impairments can significantly impact quality of life, potentially more than motor symptoms.
- Surgical intervention in complex neural circuits carries risks for cognitive and emotional well-being.
- Detailed neuropsychological evaluations are essential for risk stratification.
Conclusions:
- Careful patient selection and monitoring are vital for safe DBS procedures.
- Neuropsychological assessments aid in understanding disease mechanisms and treatment effects.
- Identifying and excluding high-risk individuals can prevent severe adverse events.
