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Updated: Jul 3, 2026

Collection of Human Follicular Fluid, Follicle Somatic Cells, and Immature Oocytes from Individuals Undergoing In Vitro Fertilization
Published on: October 24, 2025
Contribution of ovarian follicular tissue abnormalities into the development of ovarian dysfunction
S V Aidagulova1, G I Nepomnyashchikh, Yu V Galkina
1Institute of Regional Pathology and Pathomorphology, Siberian Division of Russian Academy of Medical Sciences, Novosibirsk. pathol@soramn.ru
Abstract:
Ultrastructural, in vitro radioautographic, and stereological study of the morphogenesis of ovarian cystic formations in women of reproductive age distinguished ovariopathy as a common pathological phenomenon, developing as a result of the ovarian follicular cell regenerative and plastic insufficiency syndrome. Degenerative dystrophic changes in the follicular compartment, reduced biosynthetic reactions in the follicular cells, and reactive sclerosis of the stroma remodulate the parenchyma-stromal relationships.
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