Related Experiment Video
Updated: Jul 3, 2026

12:24
Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
A moving slanted-edge method to measure the temporal modulation transfer function of fluoroscopic systems
1Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, Ontario N6A 5K8, Canada.
Medical Physics
|July 25, 2008
Summary
Lag in fluoroscopic systems can skew image quality measurements. A new method using a moving slanted edge accurately measures the temporal modulation transfer function (MTF) to correct these effects.
Area of Science:
- Medical Imaging Physics
- Radiological Sciences
- Diagnostic Imaging Technology
Background:
- Fluoroscopic systems exhibit lag, causing frame-averaging effects.
- This lag inaccurately affects image noise and detective quantum efficiency (DQE) measurements.
- Temporal modulation transfer function (MTF) measurements can correct for lag.
Purpose of the Study:
- To introduce a novel method for measuring the temporal MTF in fluoroscopic systems.
- To validate this method against direct measurements.
- To assess the impact of exposure rate on temporal MTF.
Main Methods:
- A moving slanted-edge method, generalizing the spatial MTF technique, was developed.
- The method measures the entire system's temporal MTF using a single exposure and constant edge velocity.
- Assumed separability of spatial and temporal blurring.
Main Results:
- The method demonstrated excellent agreement with direct measurements on an X-ray image intensifier (XRII) system.
- Temporal MTF was found to be dependent on exposure rate for a CsI-based system.
- Rising edges exhibited more lag than falling edges, with MTF decreasing at lower exposure rates.
Conclusions:
- The moving slanted-edge method provides accurate temporal MTF measurements for fluoroscopic systems.
- This technique is applicable to both X-ray image intensifiers and flat-panel detectors in clinical settings.
- A small-signal approach may be suitable for DQE measurements, considering lag effects.

