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Pan-dengue virus detection by PCR for travelers returning from the tropics
Alexis Dumoulin1, Hanspeter Marti, Marcus Panning
1Department of Biomedicine, Division of Diagnostics, Institute for Medical Microbiology, University of Basel, Basel, Switzerland.
Journal of Clinical Microbiology
|July 25, 2008
Abstract:
We performed dengue virus (DENV) serology and quantitative real-time pan-DENV reverse transcription-PCR (RT-PCR) on 186 sera of 171 patients returning from the tropics. DENV loads significantly decreased with increasing times of disease and were higher in immunoglobulin M-negative samples. In the first week of disease, pan-DENV RT-PCR is the test of choice.
