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Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

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Related Experiment Video

Updated: Jul 3, 2026

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

[Multiple supratentorial cavernomas and epilepsy surgery: case report].

R Rocamora¹, P Mendivil, A Schulze-Bonhage

¹Centro de Epilepsia, Universidad de Freiburg, Alemania.

Neurocirugia (Asturias, Spain)

|July 26, 2008

Summary

A single surgery successfully treated intractable epilepsy in a patient with multiple brain lesions. This highlights the effectiveness of precise surgical resection for complex seizure disorders.

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Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

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Last Updated: Jul 3, 2026

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Area of Science:

Neurosurgery
Epileptology
Neuroradiology

Background:

Epilepsy with multiple lesions necessitates thorough preoperative assessment.
Cavernous malformations can cause medically intractable seizures.

Observation:

A 56-year-old woman presented with a 26-year history of complex partial and secondarily generalized seizures.
Video electroencephalography (EEG) monitoring localized the epileptogenic zone to the left anterior temporal lobe.
Magnetic resonance imaging (MRI) revealed 9 cavernous malformations with an intact hippocampal formation.

Findings:

The patient underwent a selective resection of two adjacent cavernomas.
Post-surgery, the patient has remained seizure-free for 24 months.

Implications:

Non-invasive preoperative monitoring is crucial for diagnosing epilepsy in patients with multiple cavernous malformations.
Selective resection of affected lesions can effectively control medically intractable seizures.
This case underscores the potential for successful surgical management of complex epilepsy cases.