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Protection of H9c2 Myocardial Cells from Oxidative Stress by Crocetin via PINK1/Parkin Pathway-Mediated Mitophagy
Published on: May 26, 2023
[A myocardial infarction complicated with mitral anterior papillary muscle rupture during long-term corticotherapy]
1Service de cardiologie, hôpital du Val-de-Grâce, 74, boulevard Port-Royal, 75005 Paris, France. patrick.schiano@orange.fr
Abstract:
The authors report anterolateral papillary muscle rupture, occurring in a 67-year-old patient admitted for acute coronary syndrome. Mitral regurgitation, a rare but dramatic complication of myocardial infarction, is most often a consequence of posterior papillary muscle rupture. The 'protection' of the anterior papillary muscle is associated with vascularization via a dual coronary artery supply. Possible myocardial weakening associated with long-term corticotherapy is otherwise discussed in this observation.
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