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Updated: Jul 3, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
08:43

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

Published on: January 19, 2016

Selective ortho methylation of nitroheteroaryls by vicarious nucleophilic substitution

Michał Achmatowicz1, Oliver R Thiel, Gilles Gorins

  • 1Chemical Process Research and Development, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320-1799, USA. michala@amgen.com

The Journal of Organic Chemistry
|July 30, 2008
PubMed

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