Related Experiment Video
Updated: Jul 3, 2026
07:34
Enhancing Prostate Tumor Biobanking Reliability with Improved Sampling Technique and Histological Characterization
Published on: November 17, 2023
[Morphological parameters of prostatic adenocarcinoma]
Sandra Trivunić1, Pavle Budakov, Nada Vucković
1Institut za patologiju i histologiju, Medicinski fakultet Novi Sad, Klinicki centar Vojvodine. sanapat@eunet.yu
Medicinski Pregled
|August 1, 2008
Summary
Prostatic carcinoma is a common male malignancy. Histologic features like acinar patterns, absent basal cells, and perineural invasion aid diagnosis, with Gleason grading and immunohistochemistry crucial for prognosis.
Area of Science:
- Urology
- Oncology
- Pathology
Context:
- Prostatic carcinoma is a leading cause of cancer death in men.
- Many tumors are latent and discovered incidentally.
- Histologic patterns can mimic benign lesions.
Purpose:
- To detail the key histologic features of prostatic carcinoma.
- To highlight diagnostic challenges and tools.
Summary:
- Prostatic carcinomas exhibit distinct histologic patterns, including crowded acini, single-cell lining, absent basal cells, eosinophilic nucleoli, and perineural invasion.
- The Gleason grading system is standard for assessment.
- Immunohistochemistry is vital for diagnosis, staging, and prognosis.
Impact:
- Improved diagnostic accuracy for prostatic carcinoma.
- Enhanced understanding of histologic markers for prognosis.
- Supports clinical decision-making in prostate cancer management.
