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Regression of carotid plaques during low density lipoprotein cholesterol elimination
M Hennerici1, W Kleophas, F A Gries
1Department of Neurology, Heinrich-Heine University, Düsseldorf, FRG.
Stroke
|August 1, 1991
Abstract:
We performed serial prospective ultrasound examinations of four flat and 17 soft carotid plaques during an average of 17 months in seven patients with heterozygous hypercholesterolemia during heparin-induced extracorporeal low density lipoprotein elimination on precipitation from plasma. By means of a specially designed quantitative three-dimensional ultrasound analysis, significant plaque volume reduction could be evaluated in all subjects, along with a marked reduction of total and low density lipoprotein cholesterol and fibrinogen serum levels.