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Delayed gastric emptying in patients with caustic ingestion
Bhagwant Rai Mittal1, Rakesh Kochhar, Ravi Shankar
1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. brmittal@yahoo.com
Nuclear Medicine Communications
|August 5, 2008
Summary
Caustic ingestion significantly prolongs gastric emptying time, even without symptoms. This study assessed liquid gastric emptying using scintigraphy in patients with caustic-induced esophageal cicatrization.
Area of Science:
- Gastroenterology
- Nuclear Medicine
- Esophageal Diseases
Background:
- Caustic ingestion can lead to esophageal and gastric scarring (cicatrization).
- Gastric emptying abnormalities may occur following caustic ingestion.
- Assessing gastric emptying is crucial for understanding post-ingestion complications.
Purpose of the Study:
- To evaluate liquid gastric emptying time in patients with caustic-induced esophageal cicatrization.
- To determine if caustic ingestion affects gastric motility.
- To correlate esophageal cicatrization with gastric emptying parameters.
Main Methods:
- Radionuclide scintigraphy was used to measure liquid gastric emptying time (GET 1/2).
- Patients ingested mango juice labeled with 99mTc sulfur colloid.
- Gastric emptying was assessed over 1 hour, and results were compared to normal controls.
Main Results:
- Patients with caustic ingestion showed significantly prolonged gastric half-emptying time (GET 1/2) compared to controls (53.2 min vs. 25 min).
- Lower esophageal strictures were associated with more prolonged GET 1/2 (72.2 min).
- Prolonged gastric emptying occurred even in patients without overt gastric symptoms or gastroparesis.
Conclusions:
- Caustic ingestion leads to delayed liquid gastric emptying.
- Esophageal cicatrization, particularly in the lower third, significantly impacts gastric motility.
- Gastric emptying assessment is valuable in managing patients with caustic ingestion, even in the absence of gastric symptoms.
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