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Updated: Jul 3, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
[Laboratory tests in the elderly and their relationship with frailty]
Thomas Bertsch1, Bettina Alber, Jürgen M Bauer
1Institut für Klinische Chemie und Laboratoriumsmedizin, Klinikum Nürnberg, Prof.-Ernst-Nathan-Strasse 1, Nürnberg. thomas.bertsche@klinikum-nuernberg.de
This review explores key laboratory tests for frailty, focusing on anemia, vitamin D, thyroid, and gonadal function. Early detection and treatment of these conditions can help older adults maintain function and reduce frailty.
Area of Science:
- Geriatric Medicine
- Clinical Pathology
Context:
- Frailty is a significant geriatric syndrome increasing vulnerability in older adults.
- Identifying underlying conditions is crucial for managing frailty and functional decline.
Purpose:
- To review laboratory parameters associated with the development of frailty.
- To highlight the role of screening for specific conditions in at-risk elderly individuals.
Summary:
- The review details laboratory investigations for anemia, impaired vitamin D intake, and thyroid and gonadal dysfunction.
- These parameters are linked to the pathophysiological mechanisms underlying frailty.
Impact:
- Timely therapeutic interventions for identified conditions can stabilize elderly patients.
- This approach aims to prevent functional decline and mitigate the progression of frailty.
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