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Published on: February 28, 2017
Stimulatory constituents of Eclipta prostrata on mouse osteoblast differentiation
Mi Kyeong Lee1, Na Ry Ha, Hyekyung Yang
1College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea.
Phytotherapy Research : PTR
|August 8, 2008
Abstract:
One flavonoid, diosmetin (1), and two isoflavonoids, 3'-hydroxybiochanin A (2) and 3'-O-methylorobol (3), were isolated from the methanol extract of Eclipta prostrata L. by a bioactivity-guided fractionation technique using primary cultures of mouse osteoblasts as an in vitro assay system. All three compounds significantly increased osteoblast differentiation as assessed by the alkaline phosphatase activity..
