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Updated: Jul 2, 2026

An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes
Published on: December 25, 2021
A technical basis for the continued use of exposure as an acceptable operational quantity in radiation protection
Richard H Olsher1, Thomas D McLean, Alan L Justus
1Los Alamos National Laboratory, Los Alamos, NM 87545, USA.
Abstract:
Within the tabulated values of the new [to U.S. Department of Energy (DOE)] radiation weighting factors, it can be seen that a doubling of the neutron factor occurs for the 0.1 to 2 MeV neutron energy range. Hence, with the effective replacement of the quality factor by these new radiation weighting factors (for the protection quantities), it has been widely understood that the new changes will most definitely impact neutron dosimetry. However, it is less well understood that the new changes could also affect photon (and beta) dosimetry, i.e., photon reference fields, instrument design, and instrument calibrations. This paper discusses the ramifications, and ultimately concludes that the use of exposure for workplace measurements complies with both current and amended DOE requirements.
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