Preparation of highly photosensitizing liposomes with fullerene-doped lipid bilayer using dispersion-controllable
Atsushi Ikeda1, Tatsuya Sue, Motofusa Akiyama
1Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma 630-0192, Japan. aikeda@ms.naist.jp
Organic Letters
|August 19, 2008
Abstract:
Fullerene-containing liposomes with high photosensitization ability were prepared. Disaggregated fullerenes were efficiently injected into the bilayer of liposomes by a phototriggered molecular exchange reaction. These liposomes showed far higher photoreactivity than liposomes thermally produced by heating and microwave irradiation. This result indicates that control of self-aggregation of fullerene leads to a high quantum yield for the photoreaction because of the suppression of self-quenching of photoexcited fullerenes.
