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Updated: Jan 27, 2026
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Biotribological Testing and Analysis of Articular Cartilage Sliding against Metal for Implants
Published on: May 14, 2020
4.2K
Retrospective evaluation of patch testing before or after metal device implantation
Kurtis B Reed1, Mark D P Davis, Krystal Nakamura
1College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Archives of Dermatology
|August 20, 2008
Summary
Patch testing before metal device implantation helps guide device selection. However, patch testing after implantation showed limited value for diagnosing issues like skin eruptions or joint pain.
Area of Science:
- Allergy and immunology
- Dermatology
- Orthopedic surgery
Background:
- Metal device implantation is common in orthopedic and other surgical procedures.
- Metal allergies can cause adverse reactions, necessitating careful device selection.
- Evaluating hypersensitivity reactions to implanted metals is clinically significant.
Purpose of the Study:
- To evaluate the utility of patch testing in patients undergoing metal device implantation.
- To compare the effectiveness of patch testing performed preoperatively versus postoperatively.
Main Methods:
- Retrospective medical chart review at a tertiary care academic medical center.
- Analysis of 44 patients who underwent patch testing in conjunction with metal device implantation (22 preoperatively, 22 postoperatively).
- Patch testing was used to assess for metal allergies before implantation or to investigate adverse reactions after implantation.
Main Results:
- Preoperative patch testing identified allergies to components of proposed devices in 5 out of 22 patients.
- Postoperative patch testing was performed for unexplained skin eruptions, joint pain, or joint loosening.
- No patients undergoing postoperative patch testing had positive results for components of their previously implanted devices.
Conclusions:
- Preoperative patch testing is a valuable tool for selecting appropriate metal implants and preventing potential allergic reactions.
- Postoperative patch testing in this cohort provided limited diagnostic value for investigating implant-related symptoms.
- Further research may be needed to clarify the role of patch testing in managing adverse reactions to metal implants.
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