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Updated: Jul 2, 2026

03:57
Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
Calciphylaxis after parathyroidectomy in chronic renal failure
Muhammad A Wahab1, Fahad Al Kanhal
1Department of Nephrology, King Saud Medical Complex, Riyadh, Saudi Arabia. wahabdoc@hotmail.com
Summary
Secondary hyperparathyroidism in a long-term hemodialysis patient led to parathyroidectomy. Post-surgery, the patient developed painful ulcers, diagnosed as calciphylaxis.
Area of Science:
- Nephrology
- Endocrinology
- Dermatology
Background:
- Secondary hyperparathyroidism is a common complication in patients undergoing long-term hemodialysis.
- Parathyroidectomy is a potential treatment option for severe secondary hyperparathyroidism.
Observation:
- A 33-year-old male on hemodialysis for over 9 years presented with secondary hyperparathyroidism and a parathyroid nodule.
- The patient underwent parathyroidectomy.
- Two months post-surgery, he developed painful bilateral lower limb ulcers.
Findings:
- Skin biopsy confirmed the ulcers were consistent with calciphylaxis.
- Calciphylaxis is a rare but serious condition characterized by skin necrosis.
Implications:
- This case highlights a potential complication of parathyroidectomy in dialysis patients.
- Early recognition and management of calciphylaxis are crucial.
- Further research into the pathogenesis and prevention of calciphylaxis post-parathyroidectomy is warranted.
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