Related Experiment Video
Updated: Jul 2, 2026

Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers
Published on: June 16, 2015
Prediction of peak forces for a shortening smooth muscle tissue subjected to vibration
Ramana M Pidaparti1, Nandhini Dhanaraj, Richard A Meiss
1Department of Mechanical Engineering, Virginia Commonwealth University, Richmond, VA 23284-3015, USA. rmpidaparti@vcu.edu
Abstract:
The objective of the present study is to investigate the peak forces for a tracheal smooth muscle tissue subjected to an applied longitudinal vibration following isotonic shortening. A non-linear finite element analysis was carried out to simulate the vibratory response under experimental conditions that corresponds to forced length oscillations at 33 Hz for 1 second. The stiffness change and hysteresis estimated from the experimental data was used in the analysis. The finite element results of peak forces are compared to the experimental data obtained. The comparison of results indicate that the approach and the vibratory response obtained may be useful for describing the cross-bridge de-attachments within the cells as well as connective tissue connections characteristic of tracheal smooth muscle tissue.
Related Concept Videos
Normal Strain under Axial Loading
Thin-Walled Hollow Shafts
Elastic Strain Energy for Shearing Stresses
Smooth Muscle Contraction
The onset of contraction is triggered by an increase in calcium ions within the sarcoplasm, similar to the process in striated muscle. However, smooth muscles have a relatively smaller reservoir of the sarcoplasmic...
Flexural Stress
Hooke's Law states that within the material's elastic limits, stress is directly proportional to strain. In a member experiencing a bending moment, the strain at any point is relative to its distance...
Stresses under Combined Loadings
The process begins by slicing the tube at critical points and analyzing the internal forces and stress components at these sections, focusing on the centroid. Normal stresses, generated by axial forces and bending moments, are either compressive or tensile and vary across the section from...

