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Overview of flow cytometry instrumentation

Phillip N Dean, Robert A Hoffman

    Current Protocols in Cytometry
    |September 5, 2008
    PubMed

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    Flow Cytometry

    The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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