Related Experiment Video
Updated: Jul 1, 2026

09:04
Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
Published on: September 21, 2017
Unlocked nucleic acid (UNA) and UNA derivatives: thermal denaturation studies
Troels Bundgaard Jensen1, Niels Langkjaer, Jesper Wengel
1Nucleic Acid Center, Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark. tje@ifk.sdu.dk
Nucleic Acids Symposium Series (2004)
|September 9, 2008
Abstract:
A study on the thermal stability of duplexes formed between unlocked nucleic acid (UNA) modified DNA and RNA oligonucleotides and complementary DNA and RNA is presented. The acyclic UNA monomers are shown to induce a decrease in duplex thermal stability.

