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Updated: May 9, 2026
07:44
Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
Incorporation of cationic dyes into DNA for distinct stabilization of duplex
Hiromu Kashida1, Hidehiro Itoh, Taiga Fujii
1Graduate School of Engineering, Nagoya University, Furocho, Chikusa, Nagoya 464-8603, Japan.
Nucleic Acids Symposium Series (2004)
|September 9, 2008
Abstract:
In this study, cationic dyes (methylstilbazole) were introduced into ODN. When two complementary ODNs, both of which tethered this dye, were hybridized, the melting temperature drastically increased. The duplex was further stabilized by introducing multiple dyes.
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