Related Experiment Video
Updated: Jul 1, 2026

Histological Quantification of Chronic Myocardial Infarct in Rats
Published on: December 11, 2016
Implications of the universal definition of myocardial infarction
Joseph S Alpert1, Kristian Thygesen, Harvey D White
1University of Arizona College of Medicine, Tucson, AZ 85724, USA. jalpert@email.arizona.edu
Abstract:
The original WHO definition of myocardial infarction (MI) was revised in 2000 and further refined in 2007. Central to the new universal definition of MI was the use of the highly sensitive and specific biomarker troponin. In the investigation reviewed in this commentary, Hochholzer et al. showed that acute and long-term postinfarction prognosis and mortality were adversely affected when patients met the newly revised criteria for acute MI.
Related Concept Videos
Myocarditis I: Introduction
Acute Coronary Syndrome I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Coronary Artery Disease III: Clinical Manifestations

