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Aleukemic leukemia cutis preceding acute monocytic leukemia: a case report
Genoveva Martínez-Poventud1, Jean Fradera, Sixto Pérez
1Department of Medicine, Hematology-Medical Oncology Section, University of Puerto Rico, School of Medicine, San Juan, Puerto Rico.
Puerto Rico Health Sciences Journal
|September 12, 2008
Summary
Aleukemic leukemia cutis, a rare condition preceding acute monocytic leukemia, presents a poor prognosis. This case highlights successful treatment with chemotherapy and bone marrow transplant, achieving a six-year disease-free survival.
Area of Science:
- Hematology
- Dermatology
- Oncology
Background:
- Aleukemic leukemia cutis is a rare manifestation preceding acute leukemia, typically monocytic.
- This condition often indicates a poor prognosis and poses diagnostic challenges.
Observation:
- A 33-year-old female presented with leukemia cutis four months prior to the diagnosis of acute monocytic leukemia.
- This marks the first documented case in Puerto Rico.
Findings:
- The patient received induction and consolidation chemotherapy.
- Allogeneic bone marrow transplant was performed.
Implications:
- Successful treatment achieved a six-year disease-free remission.
- This case underscores the importance of recognizing leukemia cutis for early diagnosis and treatment of acute monocytic leukemia.
