Sclerosing panniculitis
Related Experiment Video
Updated: Jul 1, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Celia Requena1, Onofre Sanmartín, Luis Requena
1Department of Dermatology, Instituto Valenciano de Oncología, 46009 Valencia, Spain. celiareq@hotmail.com
Abstract:
Sclerosing panniculitis is a chronic panniculitis characterized by skin induration and hyperpigmentation of one or both legs that often occurs in patients who have venous insufficiency. The indurated plaques are often painful and the legs frequently have a characteristic "inverted wine bottle" appearance. Histopathology is characterized by mostly lobular panniculitis with necrosis of fat and without vasculitis, and in fully developed lesions by septal sclerosis and membranocystic changes. Treatment of sclerosing panniculitis includes compression therapy with graded stockings and anabolic steroids.
Related Concept Videos
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology
Acute Pancreatitis II: Pathophysiology
Chronic Pancreatitis II: Collaborative Care
Assessment:
Chronic Inflammation: Introduction