Composition and applications of Aloe vera leaf gel

Area of Science:

• Phytochemistry and Pharmacology
• Natural Product Research

Background:

• Aloe vera gel polysaccharides are linked to various health benefits like wound healing, antifungal, anti-diabetic, anti-inflammatory, anti-cancer, immunomodulatory, and gastroprotective properties.
• Traditional uses and known bioactivities of Aloe vera (A. vera) are well-documented.

Purpose of the Study:

• To review established biological activities of Aloe vera leaf gel.
• To highlight recently discovered applications of Aloe vera gel, focusing on enhanced bioavailability and pharmaceutical uses.

Main Methods:

• Literature review of scientific studies on Aloe vera gel.
• Analysis of research on polysaccharide bioactivity and novel applications.

Main Results:

• Aloe vera gel enhances intestinal absorption and bioavailability of co-administered substances.
• Aloe vera gel demonstrates potential for enhancing skin permeation.
• Dried Aloe vera gel powder serves as a viable excipient in sustained-release pharmaceutical dosage forms.

Conclusions:

• Aloe vera gel possesses significant potential beyond its known therapeutic properties, particularly in drug delivery and formulation.
• Further research into Aloe vera's bio-enhancement capabilities and pharmaceutical applications is warranted.