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09:54
A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
Cardiovascular changes in children with snoring and obstructive sleep apnoea
Ka-li Kwok1, Daniel K Ng, Chung-hong Chan
1Department of Paediatrics, Kwong Wah Hospital, Hong Kong SAR, China.
Annals of the Academy of Medicine, Singapore
|September 18, 2008
Summary
Childhood obstructive sleep apnoea (OSA) is linked to higher hypertension risk. This review highlights OSA
Area of Science:
- Pediatric Cardiology
- Sleep Medicine
- Cardiovascular Health
Background:
- Obstructive sleep apnoea (OSA) is a known cardiovascular risk in adults.
- Emerging evidence indicates OSA's association with cardiovascular issues in children.
- This review synthesizes current data on OSA and pediatric cardiovascular health.
Purpose of the Study:
- To examine the association between obstructive sleep apnoea and cardiovascular abnormalities in children.
- To review existing literature on the cardiovascular consequences of childhood OSA.
Main Methods:
- Systematic literature search of MEDLINE (1970-2008).
- Keywords included "child," "sleep disordered breathing," "sleep apnoea," "snoring," "blood pressure," and "hearts."
- Article selection by consensus between two authors.
Main Results:
- OSA is consistently associated with hypertension in children.
- Meta-analysis revealed a 3.15 odds ratio for hypertension in children with a high apnoea-hypopnoea index.
- Evidence suggests increased sympathetic activation, reduced arterial distensibility, and ventricular hypertrophy in children with OSA.
Conclusions:
- Childhood OSA is significantly associated with blood pressure dysregulation.
- Further research is needed to fully understand OSA's link to other cardiovascular morbidities in children.
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