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Pemphigus pain: a review on management
Rashid M Rashid1, Kenneth D Candido
1MD Anderson Cancer Center, UT, USA. rashidrashid.mdphd@yahoo.com
The Clinical Journal of Pain
|September 23, 2008
Summary
Pain management in pemphigus vulgaris is often overlooked. This review highlights the need for more research and standardized pain assessments in clinical trials for this autoimmune blistering disease.
Area of Science:
- Dermatology
- Autoimmune Diseases
- Pain Management
Background:
- Pemphigus vulgaris is an autoimmune disease characterized by painful erosions and ulcers.
- While disease remission is a focus, chronic pain is a common and significant issue for patients.
- Current literature inadequately addresses pain management strategies for pemphigus vulgaris.
Purpose of the Study:
- To review existing literature specifically on pain management in pemphigus vulgaris patients.
- To identify gaps in research regarding pain control for this condition.
Main Methods:
- A comprehensive literature search was conducted using Medline.
- Included publications encompassed case reports, reviews, and clinical trials relevant to pemphigus pain management.
Main Results:
- Pain is an underemphasized aspect of pemphigus vulgaris literature.
- Pain management approaches are predominantly based on clinical experience, not robust clinical studies.
- There is a lack of high-quality, randomized clinical studies on pain management in pemphigus.
Conclusions:
- There is a critical need for large-scale, blinded, randomized studies on pain management in pemphigus vulgaris.
- Incorporating standardized pain scale assessments in current pemphigus research would significantly enhance study outcomes and patient care.
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